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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM3
All Species:
31.82
Human Site:
Y539
Identified Species:
58.33
UniProt:
Q14832
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14832
NP_000831.2
879
98879
Y539
I
P
C
E
P
Y
E
Y
L
A
D
E
F
T
C
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
I518
H
V
C
C
F
E
C
I
D
C
L
P
G
T
F
Rhesus Macaque
Macaca mulatta
XP_001107588
879
98905
Y539
I
P
C
E
S
Y
E
Y
L
A
D
E
F
T
C
Dog
Lupus familis
XP_541867
872
95696
Y530
I
P
C
Q
P
Y
E
Y
R
L
D
E
F
T
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYS2
879
99096
Y539
I
P
C
E
P
Y
E
Y
L
V
D
E
F
T
C
Rat
Rattus norvegicus
P31422
879
98942
Y539
I
P
C
E
P
Y
E
Y
L
V
D
E
F
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515487
775
87278
S456
Q
W
P
T
S
D
L
S
G
C
F
D
L
P
E
Chicken
Gallus gallus
XP_416842
879
98936
Y539
I
P
C
E
T
Y
E
Y
L
A
D
E
F
T
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
I528
V
E
N
H
Y
S
N
I
T
D
A
D
E
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
Y589
D
S
C
E
S
F
E
Y
V
Y
D
E
F
T
C
Honey Bee
Apis mellifera
NP_001011624
933
103448
Y568
D
Q
C
E
E
Y
E
Y
V
Y
D
E
Y
T
C
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
N644
E
D
Y
E
Y
L
I
N
E
T
H
C
V
G
C
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
Y1113
I
K
C
Q
P
W
E
Y
L
Q
N
E
Y
T
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.9
99.5
68.7
N.A.
96.6
96.5
N.A.
79.1
91
N.A.
26.5
N.A.
46
48.2
39.4
33.3
Protein Similarity:
100
45.3
99.6
82.3
N.A.
98.7
98.5
N.A.
83.8
95.4
N.A.
46
N.A.
61.6
64.7
57.1
44.9
P-Site Identity:
100
13.3
93.3
80
N.A.
93.3
93.3
N.A.
0
93.3
N.A.
0
N.A.
60
60
13.3
60
P-Site Similarity:
100
13.3
93.3
86.6
N.A.
93.3
93.3
N.A.
6.6
93.3
N.A.
13.3
N.A.
73.3
73.3
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
24
8
0
0
0
0
% A
% Cys:
0
0
77
8
0
0
8
0
0
16
0
8
0
8
77
% C
% Asp:
16
8
0
0
0
8
0
0
8
8
62
16
0
0
0
% D
% Glu:
8
8
0
62
8
8
70
0
8
0
0
70
8
0
8
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
8
0
54
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% G
% His:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
54
0
0
0
0
0
8
16
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
8
0
47
8
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
8
0
0
8
0
0
0
0
% N
% Pro:
0
47
8
0
39
0
0
0
0
0
0
8
0
8
0
% P
% Gln:
8
8
0
16
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
24
8
0
8
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
8
8
0
0
0
8
8
0
0
0
77
0
% T
% Val:
8
8
0
0
0
0
0
0
16
16
0
0
8
0
0
% V
% Trp:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
16
54
0
70
0
16
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _